I just finished slicing the slide rls/lock. I left about 1/4 of it, towards the front edge, so that if I wanted, I could still use it to lock the slide back. I don't use it as a slide release, but as a slide lock.
My situation was that my firing hand's thumb would weld to the top of my non-firing hand's thumb and it would happen to occlude the slide rls/lock and put pressure upon it, such that it would defeat the magazine spring pressure pushing the empty follower against the bottom of the slide rls/lock. I do not have the problem of having large, big hands, such that my non-firing hand would push up from below the slide rls/lock.
If I did have the latter, or both these problems, I would just shave off the protruding tab, which would solve the problem 100%. It would not allow you to use thumb to lock the slide back using the rls/lock, but you easily place an empty magazine into the magwell and lock it back that way. I would have shaved the protruding rls/lock tab completely off, but I shoot in competition, and when I am unloading the gun and making it safe, I do not wish to re-insert an empty magazine into it after removing the loaded one. It would not be thoroughly appropriate and might make the RO nervous.