revchuck said:
I doubt if a bad guy would be able to tell the difference between a good hit from either.
But a BG's windshield or other cover might.
I know a lot of folks don't put a lot of stock in penetration through barriers and I completely understand. Being involved in a shooting is such a remote possibility that it may seem silly to carry a round to perform best in an even more unlikely circumstance. If you are one of those, 155 and up will surely be a good pick. If you like knowing that your bullet will have a decent chance making it through a windshield, etc. with little deflection and keeping it in one piece, I would go with 180.
Personally, I carry Winchester Ranger 180gr. RA40T's in .40.